護理師正在照顧一位有癲癇病史且服用抗癲癇藥物的病人。下列哪項指導對於預防藥物濃度驟降及潛在的癲癇復發至關重要?
A nurse is caring for a client with a history of seizures who is taking an anticonvulsant medication. Which instruction is crucial for preventing a precipitous drop in medication levels and potential breakthrough seizures?
- AReport any dizziness immediately立即報告任何眩暈
- BTake the medication with a full glass of water用一杯水送服藥物
- CDo not abruptly stop the medication✓ 正解不要突然停止用藥
- DAvoid grapefruit juice避免食用葡萄柚汁
抗癲癇藥物(Anticonvulsants)的作用機制在於維持血中藥物濃度於治療範圍內以穩定神經細胞膜。若突然中斷藥物,會導致血中濃度驟降,進而引發突破性癲癇發作(Breakthrough seizures)甚至癲癇重積狀態(Status epilepticus),後者為致命的醫療緊急狀況。病人教育的核心在於強調藥物依從性,即使症狀緩解也必須嚴格按照醫囑服藥,不可自行停藥。
The mechanism of action of anticonvulsants is to maintain blood drug levels within the therapeutic range to stabilize the neuronal cell membrane. If the medication is suddenly discontinued, blood levels drop sharply, leading to breakthrough seizures or even status epilepticus, the latter being a life-threatening medical emergency. The core of patient education is to emphasize medication adherence: even if symptoms resolve, the medication must be taken strictly according to the physician's orders and must not be discontinued on one's own.