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藥理與非經腸給藥 · MEDIUM · MCQ

一位病人被處方使用美托洛爾 (metoprolol),一種 beta-阻斷劑。哪個評估發現是給予此藥物的禁忌?

A client is prescribed metoprolol, a beta-blocker. Which assessment finding is a contraindication for administering this medication?

  • AHeart rate 48 beats/min✓ 正解
    心率 48 次/分
  • BBlood pressure 110/70 mmHg
    血壓 110/70 mmHg
  • CHeart rate 65 beats/min
    心率 65 次/分
  • DHistory of hypertension
    有高血壓病史
Explanation · 中文詳解

美托洛爾 (Metoprolol) 為選擇性 Beta-1 受體阻斷劑,主要作用為降低心率 (Negative chronotropic effect) 與心肌收縮力。若病人本身心率過緩(通常界定在 50-60 bpm 以下),給予此藥將進一步抑制竇房結功能,可能導致嚴重心搏過緩,進而影響心輸出量導致暈厥或休克。

Metoprolol is a beta-blocker that decreases heart rate and myocardial contractility, making bradycardia a primary contraindication for its administration. A heart rate of 48 beats per minute indicates significant slowing that could be exacerbated by the medication, potentially leading to hemodynamic instability, whereas a blood pressure of 110/70 mmHg is generally acceptable.

✦ 台美臨床差異

美國臨床護理實務中,對於 Beta-阻斷劑的給藥心率門檻 (Heart rate parameter) 非常嚴格,通常在給藥前會由醫師明確定義門檻,護理師需嚴格遵守,若低於門檻則必須 hold 住藥物。

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