一位病人正在接受肝素的連續輸注。護理師應監測哪個實驗室數值來評估藥物的有效性？
A client is receiving a continuous infusion of heparin. The nurse should monitor which laboratory value to assess the medication's effectiveness?
- APlatelet count血小板計數
- BPartial thromboplastin time (PTT)✓ 正解部分凝血活酶時間 (PTT)
- CBlood glucose level血糖水平
- DCreatinine肌酸酐
肝素 (Heparin) 是一種抗凝血劑，主要透過活化抗凝血酶 III (Antithrombin III) 來抑制凝血因子 IIa (Thrombin) 和 Xa。為了監測其抗凝血效果並防止過度抗凝導致的出血風險，臨床上使用活化部分凝血質時間 (aPTT) 作為監測指標。護理師需根據 aPTT 的檢驗值調整輸注速率，以維持在治療目標範圍內。
Heparin is an anticoagulant that primarily acts by activating antithrombin III, thereby inhibiting clotting factors IIa (thrombin) and Xa. To monitor its anticoagulant effect and prevent bleeding from excessive anticoagulation, the activated partial thromboplastin time (aPTT) is used clinically as the monitoring parameter. The nurse adjusts the infusion rate according to the aPTT value to keep it within the therapeutic target range.