下列哪些徵象符合鋰鹽中毒(lithium toxicity)?(選所有適合的)
Which of the following signs and symptoms are consistent with lithium toxicity? (Select all that apply.)
- ACoarse hand tremors✓ 正解粗大的手部震顫
- BConfusion and lethargy✓ 正解意識混亂與嗜睡
- CPolyuria and polydipsia多尿與多渴
- DAtaxia and incoordination✓ 正解步態不穩與協調障礙
- ESevere nausea and vomiting✓ 正解嚴重噁心與嘔吐
鋰鹽(Lithium)治療窗狹窄,血中濃度極易過高導致中毒。中毒症狀通常與神經系統毒性高度相關,包括粗大震顫(coarse tremors)、共濟失調(ataxia)、步態不穩、意識混亂(confusion)、嗜睡(lethargy)以及嚴重的腸胃道症狀(嘔吐、腹瀉)。多尿與多渴是鋰鹽的常見副作用(Side effects),而非中毒徵象。護理師需監測病人的攝取與輸出(I&O)及血中濃度,以確保在治療範圍內。
Lithium has a narrow therapeutic window, and serum concentrations can readily become elevated and produce toxicity. Symptoms of toxicity are most strongly associated with neurologic effects, including coarse tremors, ataxia, unsteady gait, confusion, lethargy, and severe gastrointestinal symptoms (vomiting, diarrhea). Polyuria and polydipsia are common side effects of lithium rather than signs of toxicity. The nurse should monitor intake and output (I&O) and the serum lithium level to ensure that the drug remains within the therapeutic range.