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藥理與非經腸給藥 · HARD · MCQ

護理師準備為一位上心室性心搏過速(SVT)病人施打 Adenosine 6 mg。護理師應如何給藥?

A nurse is preparing to administer adenosine 6 mg to a client with supraventricular tachycardia (SVT). How should the nurse administer this medication?

  • AAdminister as a rapid bolus over 1 to 2 seconds followed by a saline flush✓ 正解
    在 1 至 2 秒內快速推注,隨後以生理食鹽水沖管
  • BAdminister over 2 to 3 minutes using a slow IV push
    使用慢速靜脈推注,時間為 2 至 3 分鐘
  • CDilute in 50 mL of normal saline and infuse via secondary tubing
    稀釋於 50 mL 生理食鹽水中,透過次要管路輸注
  • DGive via the intramuscular route into a large muscle mass
    透過肌肉注射途徑注入大塊肌肉
Explanation · 中文詳解

Adenosine 的藥物半衰期極短(少於 10 秒)。為了使其能在代謝掉之前到達心臟發揮藥效,必須採取「極快速靜脈推注」(Rapid IV push),時間控制在 1-2 秒內。推注後應立即跟隨 20 mL 的生理食鹽水沖洗(Saline flush),並最好將給藥肢體抬高,以利用重力加速藥液進入循環。B 選項(慢推)會使藥物在到達心臟前就被完全代謝。C 選項(稀釋點滴)無效。D 選項(肌肉注射)完全錯誤。這題考的是護理師對藥物動力學與特殊給藥技術的掌握,這是處理致命性心律不整的關鍵技能。

Adenosine has an extremely short half-life (less than 10 seconds). To allow the drug to reach the heart before being metabolized, it must be administered as a rapid IV push within 1-2 seconds. Immediately afterward, it should be followed by a 20 mL normal saline flush, and ideally the administering extremity should be elevated so that gravity speeds the drug into the central circulation. Option B (slow push) results in the drug being fully metabolized before reaching the heart. Option C (diluted infusion) is ineffective. Option D (intramuscular injection) is completely incorrect. This item tests the nurse's mastery of pharmacokinetics and special drug-administration techniques, which is a critical skill in managing life-threatening dysrhythmias.

✦ 台美臨床差異

美國 NCLEX 與 ACLS 指引高度一致,強調「快速推注 + 抬高手臂」;台灣臨床通常由醫師親自推注 Adenosine,護理師負責備藥與沖水,但護理師仍需熟悉此特殊技術以協助急救。

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