— 藥理與非經腸給藥 · MEDIUM · MCQ —
病人因感染使用 Gentamicin。護理師應優先監測下列哪項發現？
A client with an infection is prescribed gentamicin. The nurse should prioritize monitoring for which assessment finding?
- AIncreased urinary output尿量增加
- BDevelopment of a skin rash出現皮膚紅疹
- CElevated white blood cell count白血球計數升高
- DChange in serum creatinine levels✓ 正解血清肌酸酐數值變化
— Explanation · 中文詳解 —
Gentamicin 屬於胺基糖苷類（aminoglycoside）抗生素，具有明確的腎毒性（nephrotoxicity）與耳毒性（ototoxicity）。在治療期間，護理師必須嚴密監測腎功能指標，其中肌酸酐（serum creatinine）數值的變化最能反映 Gentamicin 對腎臟的累積性損害。若數值上升，可能需要調整劑量或停藥，以預防藥物引起的腎衰竭。
Gentamicin is an aminoglycoside with well-documented nephrotoxicity and ototoxicity. During therapy, the nurse must monitor renal function closely; serum creatinine best reflects cumulative renal injury from gentamicin. Rising values may require dose adjustment or discontinuation to prevent drug-induced renal failure.