— 藥理與非經腸給藥 · MEDIUM · MCQ —
護理師準備給予病人 Warfarin。應檢視哪項實驗室數值以評估治療效果？
A nurse is preparing to administer warfarin to a client. Which laboratory value should the nurse review to determine the effectiveness of the therapy?
- AActivated partial thromboplastin time (aPTT)活化部分凝血活酶時間 (aPTT)
- BProthrombin time (PT)凝血酶原時間 (PT)
- CPlatelet count血小板計數
- DInternational normalized ratio (INR)✓ 正解國際標準化比值 (INR)
— Explanation · 中文詳解 —
Warfarin（Coumadin）影響維生素 K 依賴性凝血因子，臨床監測以 INR 為標準。雖然 PT 也會受影響，但 INR 是國際標準化比值，能消除實驗室檢測差異，是評估該藥物治療窗口的核心指標。
Warfarin affects vitamin K-dependent clotting factors, and the International Normalized Ratio (INR) is the standardized test used to monitor its therapeutic effectiveness. While prothrombin time (PT) is also affected, INR eliminates variability between laboratories to ensure accurate dosing adjustments.
✦ 台美臨床差異
美台兩地臨床皆一致使用 INR 作為 Warfarin 療效監測指標。