— 藥理與非經腸給藥 · MEDIUM · MCQ —
一位病人使用華法林(Warfarin)治療。下列何種檢驗數值顯示藥物達到治療範圍?
A client is prescribed warfarin therapy. Which laboratory result indicates that the medication is at a therapeutic level?
- AINR 2.0 to 3.0✓ 正解INR 2.0 至 3.0
- BPT 10 to 12 secondsPT 10 至 12 秒
- CPlatelet count 150,000 to 400,000血小板計數 150,000 至 400,000
- DPTT 60 to 80 secondsPTT 60 至 80 秒
— Explanation · 中文詳解 —
華法林主要監測國際標準化比值(INR)。對於大多數需長期抗凝血的適應症(如心房顫動、深部靜脈栓塞),治療範圍通常設定在 2.0 到 3.0 之間。PT 與 PTT 是凝血時間,PTT 用於監測肝素(Heparin),PT 雖是華法林基礎,但目前臨床標準皆以 INR 為準。
Warfarin therapy is monitored using the International Normalized Ratio (INR), with a standard therapeutic range of 2.0 to 3.0 for most indications such as atrial fibrillation or deep vein thrombosis. While prothrombin time (PT) is related, the INR provides a standardized measurement for anticoagulation effectiveness. Other values like platelet counts or partial thromboplastin time (PTT) are not used to monitor warfarin levels.
✦ 台美臨床差異
台灣與美國對 INR 的監測目標一致,皆由藥師或醫師調整劑量,護理師負責採檢與衛教。