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降低風險 · EASY · MCQ

護理師正在照顧一位因深部靜脈栓塞接受肝素(heparin)點滴注射的病人。護理師應監測哪項檢驗數值以調整劑量?

A nurse is caring for a client who is receiving a heparin infusion for a deep vein thrombosis. Which laboratory value should the nurse monitor to adjust the dosage?

  • AInternational Normalized Ratio (INR)
    國際標準化比值(INR)
  • BPlatelet count
    血小板計數
  • CActivated partial thromboplastin time (aPTT)✓ 正解
    活化部分凝血活酶時間(aPTT)
  • DProthrombin time (PT)
    凝血酶原時間(PT)
Explanation · 中文詳解

肝素(Heparin)主要作用於內源性凝血途徑,其治療效果通常使用 aPTT 來監測,治療範圍通常為正常值的 1.5 到 2.5 倍。PT/INR 用於監測口服抗凝血劑 warfarin。血小板計數雖重要(監測 HIT),但非調整劑量的主要依據。

The activated partial thromboplastin time (aPTT) is the primary laboratory value used to monitor the therapeutic effect of intravenous heparin and adjust the dosage. Heparin affects the intrinsic coagulation pathway, which is measured by aPTT. In contrast, the prothrombin time (PT) and International Normalized Ratio (INR) are used to monitor warfarin therapy.

✦ 台美臨床差異

美國臨床多使用標準化 Heparin Protocol(含 aPTT 或 Anti-Xa);台灣醫院亦有類似 protocol,但調整權限多需確認醫囑。

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