— 藥理與非經腸給藥 · MEDIUM · MCQ —
護理師準備給予病人長效型胰島素（Glargine）與短效型胰島素（Regular）。哪項操作是正確的？
A nurse is preparing to administer insulin glargine and regular insulin to a client. Which action is correct?
- ADraw up regular insulin first, then glargine先抽取常規胰島素，再抽取甘精胰島素
- BInject both insulins into the same site consecutively連續在同一個部位注射兩種胰島素
- CMix them in the same syringe to minimize injections將兩者混合於同一支針筒中以減少注射次數
- DAdminister each insulin in separate syringes at different sites✓ 正解使用不同的針筒在不同的部位分別給予胰島素
— Explanation · 中文詳解 —
胰島素給藥需注意藥物動力學與物理化學特性。長效型胰島素 Glargine（Lantus）的 pH 值呈現酸性，若與其他種類（如 Regular insulin）混合在同一針筒中，會導致藥物沉澱，不僅影響藥效發揮的穩定性，還可能導致吸收速率改變。因此，臨床規範要求必須分開針筒、分開部位注射，以確保劑量準確與療效。
Insulin glargine is incompatible with other insulins because its acidic pH causes precipitation when mixed, altering absorption and efficacy. Therefore, it must be administered separately using distinct syringes and injection sites to ensure accurate dosing and safety.