病人正接受肝素 (Heparin) 持續滴注。護理師應監測哪項檢驗數據？

Heparin 是一種抗凝血劑，其作用機轉是增強抗凝血酶 III（Antithrombin III）的活性，從而抑制凝血酶的產生。由於 Heparin 主要影響內源性凝血路徑（Intrinsic pathway），臨床上監測其治療效果的黃金標準是活化部分凝血活酶時間（aPTT）。護理師需根據實驗室數值與醫師的給藥流程（Nomogram）調整輸注速度，以維持治療性區間，避免出血或栓塞風險。

Heparin is an anticoagulant whose mechanism is to enhance the activity of antithrombin III, thereby inhibiting thrombin generation. Because heparin primarily affects the intrinsic pathway of coagulation, the gold standard for monitoring its therapeutic effect is the activated partial thromboplastin time (aPTT). The nurse must adjust the infusion rate according to laboratory values and the physician's dosing nomogram to maintain the therapeutic range and avoid bleeding or thrombosis.