— 藥理與非經腸給藥 · HARD · SATA —
護理師監測使用氨基糖苷類（Aminoglycoside）藥物的病人，哪些檢驗數值應優先關注？（選所有適合的）
A nurse is monitoring a client on aminoglycoside therapy. Which lab values should be prioritized? (Select all that apply.)
- ACreatinine level✓ 正解肌酸酐濃度
- BBUN level✓ 正解BUN 濃度
- CPeak and trough levels✓ 正解峰值與谷值濃度
- DWhite blood cell count白血球計數
- ESerum potassium level血清鉀濃度
— Explanation · 中文詳解 —
Aminoglycoside 具有腎毒性與耳毒性。監測腎功能指標（Creatinine, BUN）可評估腎排泄能力，避免蓄積中毒。此外，此藥具狹窄治療指數，必須監測藥物血中濃度（Peak and trough levels）以調整劑量。白血球用於評估感染控制狀況，鉀則非此類藥物主要影響指標。
Aminoglycosides are nephrotoxic and ototoxic, requiring close monitoring of renal function via creatinine and BUN levels to prevent drug accumulation. Additionally, peak and trough serum levels must be tracked due to the drug's narrow therapeutic index to ensure efficacy while minimizing toxicity.
✦ 台美臨床差異
兩地醫院對於 Peak/Trough 濃度追蹤皆由藥師與醫師共同合作，護理師則負責精準採血時間。