— 藥理與非經腸給藥 · EASY · MCQ —
下列哪種藥物需要護理師在給藥前測量心尖脈整整一分鐘？
Which of the following medications requires the nurse to assess the apical pulse for one full minute before administration?
- ALisinoprilLisinopril（賴諾普利）
- BDigoxin✓ 正解Digoxin（地高辛）
- CMetoprololMetoprolol（美托洛爾）
- DAmlodipineAmlodipine（氨氯地平）
— Explanation · 中文詳解 —
毛地黃類藥物（Digoxin）具有正性肌力與負性變時作用（減慢心跳）。由於其治療窗（Therapeutic window）狹窄，且極易產生毒性反應（Digitalis toxicity），在心跳過慢（通常成人小於 60 bpm）時給藥會加重危險。因此，給藥前必須測量心尖脈整整一分鐘，以確保心率在安全範圍內。
Digoxin has a narrow therapeutic index and can cause toxicity, including severe bradycardia; therefore, the nurse must assess the apical pulse for one full minute before administration. If the heart rate is below 60 bpm in an adult, the dose should be withheld to prevent dangerous cardiac effects.