護理師指導病人使用 alendronate 治療骨質疏鬆。應包含哪些衛教內容？（選所有適合的）
A nurse is teaching a client who has been prescribed alendronate for osteoporosis. Which instructions should the nurse include? (Select all that apply.)
- ATake the medication with a full glass of water✓ 正解以一杯滿的水送服藥物
- BRemain upright for at least 30 minutes after taking✓ 正解服藥後至少保持直立姿勢30分鐘
- CTake the medication with breakfast to prevent stomach upset隨早餐服用藥物以預防胃部不適
- DReport any difficulty swallowing or chest pain✓ 正解若出現吞嚥困難或胸痛應立即回報
- ETake the medication immediately upon waking in the morning✓ 正解於早晨醒來時立即服用藥物
Alendronate 屬於雙磷酸鹽類，對食道有強烈刺激性，可能導致食道潰瘍。正確服藥方式為起床空腹服用，搭配一大杯白開水，且服藥後 30 分鐘內不得躺臥或進食，以確保藥物順利進入胃部並減少逆流傷害。C 是錯誤的，與食物共服會顯著降低吸收率。
Alendronate is a bisphosphonate that is strongly irritating to the esophagus and may cause esophageal ulceration. The correct administration is upon awakening on an empty stomach, taken with a full glass of plain water; the client must not lie down or eat within 30 minutes after dosing so that the drug enters the stomach smoothly and reflux injury is minimized. Option C is incorrect because taking the medication with food significantly reduces absorption.
美台對此藥的衛教重點完全一致，強調預防食道炎是護理衛教的關鍵項目。