哪些評估顯示重度憂鬱症病人對 fluoxetine 治療有正向反應？（選所有適合的）
Which of the following assessments indicate a client with major depressive disorder is experiencing a positive therapeutic response to fluoxetine? (Select all that apply.)
- AIncreased interest in personal hobbies✓ 正解對個人愛好興趣增加
- BAbility to sleep through the night✓ 正解能夠整夜安睡
- CReported increase in energy levels✓ 正解報告能量水平增加
- DImproved concentration at work✓ 正解工作時的注意力改善
- EOccasional feelings of sadness偶爾感到悲傷
抗憂鬱劑（如 SSRI）的療效評估在於核心症狀的緩解，包括快感缺失的改善、睡眠品質提升、精神能量恢復及認知功能的改善。偶爾感到悲傷（選項 E）屬於正常的範圍內的情緒起伏，並非憂鬱症狀惡化或治療無效之證據，因此不作為評估指標。
The therapeutic evaluation of antidepressants (such as SSRIs) is based on the relief of core symptoms, including improvement in anhedonia, improvement in sleep quality, restoration of mental energy, and improvement in cognitive function. Occasional feelings of sadness (option E) fall within the normal range of mood fluctuation and do not constitute evidence of worsening depressive symptoms or treatment failure; therefore, this is not used as an indicator of evaluation.
台灣醫師常合併安眠藥使用，護理師評估重點需區分是藥物帶來的困倦還是憂鬱症緩解；美國則較強調 SSRI 的單一藥效評估。