— 藥理與非經腸給藥 · MEDIUM · MCQ —
病人正接受華法林（Warfarin）抗凝血治療，護理師評估時應優先檢視哪項檢驗數據？
A client is prescribed warfarin therapy. Which laboratory value should the nurse prioritize during assessment?
- AActivated Clotting Time (ACT)活化部分凝血活酶時間 (ACT)
- BPlatelet Count血小板計數
- CInternational Normalized Ratio (INR)✓ 正解國際正常化比值 (INR)
- DPartial Thromboplastin Time (PTT)部分凝血活酶時間 (PTT)
— Explanation · 中文詳解 —
華法林作用於維生素 K 依賴性凝血因子，其監測指標為 INR。治療範圍通常設定在 2.0-3.0 之間（視病況而定）。PTT 是監測肝素（Heparin）的指標，兩者不可混淆，否則會導致嚴重的抗凝血劑過量或不足。
Warfarin acts on vitamin K-dependent clotting factors, and its monitoring parameter is the INR. The therapeutic range is typically 2.0-3.0, depending on the clinical indication. PTT is the monitoring parameter for heparin, and the two must not be confused, as this could lead to serious overdose or underdosing of anticoagulant therapy.
✦ 台美臨床差異
台美皆依據 INR 調整劑量，但在台灣基層診所，華法林衛教與監測常由醫師親自進行，美國則多有抗凝血劑門診由專業藥師或護理師共同監控。