— 藥理與非經腸給藥 · EASY · MCQ —
病人因二型糖尿病服用 Metformin。哪項臨床表現暗示藥物有效？
A client is taking Metformin for Type 2 diabetes. Which clinical indication suggests the medication is effective?
- AWeight loss of 10 lbs in one month一個月內減重 10 磅
- BHbA1c level of 6.5%✓ 正解HbA1c 水平為 6.5%
- CReduced need for insulin減少對胰島素的需求
- DIncreased energy levels增加能量水平
— Explanation · 中文詳解 —
糖尿病控制的核心目標是長期血糖穩定，HbA1c（糖化血色素）是反映過去 2-3 個月平均血糖的最佳指標。Metformin 能降低血糖，若 HbA1c 數值達標（如 6.5%），即代表控制良好。體重減輕或能量提升為次要觀察項目。
The core goal of diabetes management is sustained glycemic control over time. HbA1c (glycated hemoglobin) is the best indicator of average blood glucose over the past 2-3 months. Metformin lowers blood glucose, and an HbA1c value at goal (e.g., 6.5%) reflects good control. Weight loss or increased energy are secondary observations.
✦ 台美臨床差異
台灣健保給付亦以 HbA1c 作為糖尿病藥物調整的依據，兩地臨床評估標準一致。