— 藥理與非經腸給藥 · MEDIUM · MCQ —
一位慢性腎臟病（CKD）病人使用 Epoetin alfa。下列何種發現顯示該藥物發揮療效？
A client with chronic kidney disease (CKD) is prescribed epoetin alfa. Which findings indicate the medication is effective?
- AIncreased serum creatinine血清肌酸酐增加
- BImproved appetite and weight gain食慾改善和體重增加
- CIncreased hemoglobin and hematocrit✓ 正解血色素和血容積增加
- DDecreased blood pressure血壓降低
— Explanation · 中文詳解 —
Epoetin alfa 是一種人工合成的紅血球生成素，用於治療慢性腎病（CKD）病人因腎臟分泌不足而引發的貧血。其藥理機轉是刺激骨髓產生紅血球。療效的評估指標為血紅素（Hemoglobin, Hb）與血容比（Hematocrit, Hct）的上升。護理師需監測這些數值，以確保藥物有效並避免過度治療導致的併發症。
Epoetin alfa is a synthetic erythropoietin used to treat anemia caused by inadequate renal production in CKD clients. It stimulates the bone marrow to produce red blood cells. Therapeutic effectiveness is evaluated by a rise in hemoglobin (Hgb) and hematocrit (Hct). The nurse must monitor these values to confirm efficacy and avoid complications of over-treatment.