— 藥理與非經腸給藥 · MEDIUM · MCQ —
病人獲開立碳酸鋰 (Lithium Carbonate)。哪項檢驗數值監測最為關鍵？
A client is prescribed lithium carbonate. Which lab value is critical to monitor?
- AWhite blood cell count白血球計數
- BCreatinine level肌酸酐濃度
- CSerum sodium level血清鈉濃度
- DSerum lithium level✓ 正解血清鋰濃度
— Explanation · 中文詳解 —
碳酸鋰（Lithium Carbonate）是一種情緒穩定劑，其治療指數（Therapeutic index）非常狹窄，這意味著治療濃度與中毒濃度極為接近。因此，定期監測血清鋰濃度（Serum lithium level）是確保藥物安全與療效的核心行動。鋰的代謝與鈉離子及腎功能密切相關，但判斷是否中毒的基準點仍是血清濃度。
Lithium carbonate has a narrow therapeutic index, meaning the difference between a therapeutic dose and a toxic dose is very small. Therefore, monitoring serum lithium levels is critical to ensure safety and efficacy. While sodium levels and renal function influence lithium metabolism, the serum lithium concentration is the primary indicator for preventing toxicity.