— 藥理與非經腸給藥 · EASY · MCQ —
護理師準備給予深部靜脈栓塞病史的病人服用 Warfarin。給藥前應檢視哪項檢驗數值?
A nurse is preparing to administer warfarin to a client with a history of deep vein thrombosis. Which laboratory value should the nurse review prior to administration?
- AProthrombin time (PT) and INR✓ 正解凝血酶原時間 (PT) 和國際標準化比值 (INR)
- BHemoglobin and hematocrit血紅素和血球容積比
- CPartial thromboplastin time (PTT)部分凝血活酶時間 (PTT)
- DPlatelet count血小板計數
— Explanation · 中文詳解 —
Warfarin 是維生素 K 拮抗劑,其抗凝血效應是透過抑制凝血因子合成達成的,臨床監測指標為 PT 值與 INR。若 INR 超出治療範圍(通常為 2.0-3.0),給藥可能導致嚴重的出血危險,護理師需確認該指標以決定是否給藥。
Warfarin is a vitamin K antagonist whose anticoagulant effect comes from inhibiting clotting factor synthesis. The clinical monitoring values are PT and INR. If INR is outside the therapeutic range (typically 2.0-3.0), administering the drug may cause serious bleeding; the nurse must verify this value before giving the dose.
✦ 台美臨床差異
台美均使用 INR 作為 Warfarin 監測標準,台灣各醫院對處方決策的指引相似。