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生理適應 · EASY · MCQ

下列哪位病患發生低血鈉的風險最高?

Which of the following clients is at the highest risk for developing hyponatremia?

  • AClient on long-term steroid therapy
    接受長期類固醇治療的個案
  • BClient with chronic diarrhea
    患有慢性腹瀉的個案
  • CClient with diabetes insipidus
    患有尿崩症的個案
  • DClient with SIADH✓ 正解
    患有抗利尿激素分泌不當症候群(SIADH)的個案
Explanation · 中文詳解

低血鈉(hyponatremia)的最高風險族群分析:C. SIADH(抗利尿激素分泌失調症候群)導致 ADH 過度分泌,腎臟過度保留水分而引發稀釋性低血鈉,是最直接、最高風險的疾病。其他選項:B. 慢性腹瀉造成 isotonic 體液流失(鈉與水同時流失),可能導致低血容量但血鈉常維持正常或輕度變化;B. 長期類固醇(皮質醇有 mineralocorticoid 作用)會引起鈉滯留與水分滯留,傾向高血鈉而非低血鈉;D. Diabetes insipidus(尿崩症)因 ADH 不足造成大量稀釋尿,反而是高血鈉的高風險。

Analysis of the highest-risk population for hyponatremia: C. SIADH (syndrome of inappropriate antidiuretic hormone secretion) causes excessive ADH secretion, leading the kidneys to retain water and producing dilutional hyponatremia—it is the most direct and highest-risk condition. Other options: A. Chronic diarrhea causes isotonic fluid loss (sodium and water are lost together), which may produce hypovolemia but sodium typically remains normal or only mildly altered; B. Long-term steroid therapy (cortisol has mineralocorticoid activity) causes sodium and water retention, trending toward hypernatremia rather than hyponatremia; D. Diabetes insipidus, due to insufficient ADH, results in massive dilute urine output, which is a high risk for hypernatremia.

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