對於服用硝酸甘油(Nitroglycerin)舌下錠的病人,下列哪項指導是合適的?
Which of the following is an appropriate instruction for a client taking Nitroglycerin sublingual tablets?
- ASwallow the tablet with a full glass of water用一杯水吞服藥片
- BStore the medication in a clear bottle in direct sunlight將藥物存放在陽光直射的透明瓶中
- CPlace one tablet under the tongue every 5 minutes for up to 3 doses✓ 正解每 5 分鐘舌下含服一片,最多三劑
- DTake the medication only when you feel intense chest pain僅在感到劇烈胸痛時服藥
硝酸甘油(Nitroglycerin)舌下錠透過舌下黏膜迅速吸收,直接進入血液循環,避開肝臟的首過效應(first-pass effect),用於緩解心絞痛。正確用法為置於舌下含服,不可吞服。藥物保存對效價至關重要,應放置於原裝遮光瓶中,避免受潮、光照與高溫。若胸痛發作時,應遵循每 5 分鐘含服一次、最多 3 次的原則,若症狀未緩解,需立即送醫。
Sublingual nitroglycerin tablets are rapidly absorbed through the sublingual mucosa and enter the bloodstream directly, bypassing hepatic first-pass metabolism, in order to relieve angina. The correct method is to place the tablet under the tongue and not swallow it. Storage is essential to potency: tablets should be kept in their original light-protected bottle, away from moisture, light, and heat. When chest pain occurs, the client should follow the principle of one tablet every 5 minutes for up to 3 doses; if symptoms are not relieved, emergency medical services should be sought immediately.