— 藥理與非經腸給藥 · MEDIUM · MCQ —
護理師正準備給予哌拉西林-他唑巴坦（piperacillin-tazobactam）的靜脈輸注。應最優先監測哪個潛在的副作用？
A nurse is preparing to administer an IV infusion of piperacillin-tazobactam. Which potential adverse effect is most important to monitor for?
- AHypoglycemia低血糖
- BConstipation便秘
- CBradycardia心動過緩
- DAllergic reaction✓ 正解過敏反應
— Explanation · 中文詳解 —
哌拉西林-他唑巴坦屬於廣效性盤尼西林類抗生素。盤尼西林類藥物最嚴重的潛在副作用是過敏反應（Allergic reaction），從輕微皮膚紅疹到致命的過敏性休克（Anaphylaxis）皆有可能發生。護理師在給藥前必須確認病人有無盤尼西林過敏史，並在給藥後觀察有無呼吸困難、喉頭水腫等過敏徵兆，這是病人安全監測的最優先項目。
Piperacillin-tazobactam is a broad-spectrum penicillin-class antibiotic, making allergic reactions, including potentially fatal anaphylaxis, the most critical adverse effect to monitor. Nurses must assess for a history of penicillin allergy before administration and closely observe the patient for signs such as respiratory distress or laryngeal edema immediately following the infusion.