— 藥理與非經腸給藥 · EASY · MCQ —
護理師準備對病人給予華法林（Warfarin）。給藥前應評估哪一項檢驗數值？
A nurse is preparing to administer warfarin to a client. Which laboratory value should the nurse evaluate before administration?
- AaPTT活化部分凝血活酶時間
- BPlatelet count血小板計數
- CHgb and Hct血色素與血球容積比
- DPT/INR✓ 正解凝血酶原時間/國際標準化比值
— Explanation · 中文詳解 —
華法林為維生素 K 拮抗劑，主要透過抑制凝血因子合成發揮作用。臨床上透過監測凝血酶原時間及其國際標準化比值（PT/INR）來調整劑量，以確保抗凝血效果並防止出血風險。PTT 是監測肝素（Heparin）的指標，兩者不可混淆。
Warfarin is a vitamin K antagonist that works primarily by inhibiting the synthesis of clotting factors. Clinically, the prothrombin time and its international normalized ratio (PT/INR) are monitored to adjust dosing, ensuring anticoagulant effect while minimizing bleeding risk. PTT is used to monitor heparin, and the two should not be confused.
✦ 台美臨床差異
兩地皆使用 INR 做為華法林監測指標，臨床照護原則完全一致。