一位慢性阻塞性肺病（COPD）病人正使用鼻導管給氧。哪種 SpO2 範圍最合適？

慢性阻塞性肺病（COPD）病人的呼吸中樞對二氧化碳（CO2）的敏感度降低，呼吸驅動力改為依賴缺氧（Hypoxia）刺激，此即所謂的「缺氧驅動呼吸」（Hypoxic drive）。若給予過高濃度的氧氣，會使血液中的氧分壓過高，從而抑制呼吸中樞，導致病人呼吸變淺、頻率降低，進而引發二氧化碳滯留（CO2 Narcosis）。因此，針對這類病人，目標 SpO2 通常設定在 88-92% 之間，以維持適當的氧合且不抑制呼吸驅動。

Clients with COPD often rely on hypoxic drive rather than hypercapnic drive to stimulate respiration because their respiratory centers have reduced sensitivity to carbon dioxide. Administering high concentrations of oxygen can suppress this drive, leading to hypoventilation, carbon dioxide retention, and narcosis. Therefore, the target SpO2 range is typically set between 88% and 92% to maintain adequate oxygenation without inhibiting the respiratory center.