— 藥理與非經腸給藥 · EASY · MCQ —
一位病人正在接受肝素（Heparin）持續點滴輸注。護理師應監測哪項實驗室數值以評估治療效果？
A client is receiving a continuous heparin infusion. Which laboratory value should the nurse monitor to evaluate the effectiveness of the therapy?
- AActivated partial thromboplastin time (aPTT)✓ 正解活化部分凝血活酶時間 (aPTT)
- BPlatelet count血小板計數
- CProthrombin time (PT)凝血酶原時間 (PT)
- DInternational Normalized Ratio (INR)國際標準化比值 (INR)
— Explanation · 中文詳解 —
肝素主要作用於內源性凝血路徑，臨床上常使用 aPTT 來監測其治療範圍內的抗凝血效果。PT 和 INR 是用來監測華法林（Warfarin）的指標。血小板計數雖需監測以預防肝素引起的血小板低下（HIT），但非評估藥物抗凝效果的指標。
Activated partial thromboplastin time (aPTT) is the standard laboratory test for monitoring the therapeutic effectiveness of continuous heparin infusions, as heparin affects the intrinsic coagulation pathway. While platelet counts are monitored to detect heparin-induced thrombocytopenia, they do not measure anticoagulant efficacy, and PT/INR are used for warfarin monitoring.
✦ 台美臨床差異
台美兩地皆以 aPTT 為標準，但台灣醫療單位常透過電腦醫令系統自動連線更新採血時程。