— 藥理與非經腸給藥 · EASY · MCQ —
護理師準備對一位有深層靜脈栓塞病史的病人給予華法林(Warfarin)。給藥前應檢視哪項實驗室數據?
A nurse is preparing to administer warfarin to a client with a history of deep vein thrombosis. Which laboratory value should the nurse review before administering the dose?
- APlatelet count血小板計數
- BaPTT活化部分凝血活酶時間
- CHemoglobin血紅素
- DPT/INR✓ 正解凝血酶原時間/國際標準比值
— Explanation · 中文詳解 —
華法林(Warfarin)是一種維生素 K 拮抗劑,影響外源性凝血路徑,臨床上使用國際標準化比率(INR)與凝血酶原時間(PT)來監測藥效。若 INR 超過治療範圍(通常為 2.0-3.0),給藥可能會導致嚴重的出血風險。
Warfarin is a vitamin K antagonist that affects the extrinsic coagulation pathway, requiring monitoring via Prothrombin Time (PT) and International Normalized Ratio (INR). An INR exceeding the therapeutic range, typically 2.0 to 3.0, significantly increases the risk of severe bleeding, making this the priority laboratory value to review before administration.
✦ 台美臨床差異
台美醫師皆會依據 INR 調整劑量,但在台灣基層診所,華法林管理常結合慢性病連續處方箋制度進行追蹤。