一位病人被處方定期給予賴諾普利 (lisinopril)，一種 ACE 抑制劑。哪個評估發現會要求護理師暫停給藥並通知醫護人員？

血管收縮素轉換酶抑制劑（ACE inhibitor）透過抑制 ACE 酵素，減少血管收縮素 II 的生成而達到降血壓效果。此藥物最危險的嚴重副作用是血管性水腫（angioedema），其機轉與緩激肽（bradykinin）堆積導致血管通透性增加有關。血管性水腫可迅速進展至喉頭水腫、呼吸道阻塞，屬於致命性的緊急情況，護理師發現此症狀必須立即停藥並通知醫師進行氣道評估與急救處置。

Angioedema is a rare but potentially life-threatening adverse reaction to ACE inhibitors caused by bradykinin accumulation. It can rapidly progress to upper airway obstruction, requiring immediate discontinuation of the medication and emergency intervention. While a dry cough is a common side effect, it does not typically warrant holding the dose unless severe.