為預防醫療機構內困難梭狀芽孢桿菌（C. difficile）的傳播，護理師應優先採取哪項行動？
Which action should the nurse prioritize to prevent the transmission of Clostridioides difficile in a healthcare setting?
- APlace the client in a negative pressure isolation room將病人安置於負壓隔離病房
- BWear a N95 respirator when entering the room進入病房時佩戴 N95 口罩
- CPerform hand hygiene with soap and water after patient contact✓ 正解接觸病人後用肥皂和水進行手部衛生
- DUse alcohol-based hand sanitizer after patient contact接觸病人後使用含酒精的乾洗手液
困難梭狀芽孢桿菌（Clostridioides difficile, C. diff）感染的預防核心在於機械性移除。由於其芽孢（Spore）結構對酒精具備極強的抵抗力，一般的酒精性乾洗手無法將其消滅，反而可能透過摩擦將芽孢散佈至其他區域。因此，臨床規範明確要求在接觸病人後，必須使用肥皂與流動水洗手，以達到物理移除的效果。
Hand hygiene with soap and water is the critical action to prevent Clostridioides difficile transmission because mechanical friction effectively removes spores that are resistant to alcohol-based sanitizers. Negative pressure rooms and N95 respirators are reserved for airborne precautions, which do not apply to this contact-spread pathogen. Alcohol sanitizers fail to kill C. difficile spores and may spread them via contamination.
台美臨床對於 C. diff 的防護均高度一致，皆嚴格執行接觸隔離（Contact Precautions）並強調肥皂洗手。美國醫院通常會在其隔離標誌上明確標示「Soap and Water Only」以提醒醫護人員。