— 藥理與非經腸給藥 · MEDIUM · MCQ —
護理師給予「治療指數狹窄」的藥物，這代表什麼？
A nurse is administering a medication with a narrow therapeutic index. What does this mean?
- AThe medication is easily excreted該藥物容易經排泄清除
- BThe medication is ineffective in most cases該藥物在大多數情況下無效
- CThe drug does not require monitoring該藥物不需要監測
- DThe difference between effective and toxic dose is small✓ 正解有效劑量與中毒劑量之間的差異很小
— Explanation · 中文詳解 —
治療指數（Therapeutic Index）狹窄的藥物，代表其「有效治療濃度」與「中毒濃度」之間的範圍非常小。這類藥物（如 Digoxin, Lithium, Warfarin）在臨床使用時，即便劑量微調都可能導致嚴重的毒性反應。護理師需監測病人的血中濃度（Serum drug levels）以及藥物中毒的臨床徵兆，以確保安全。
A narrow therapeutic index means there is a small margin between the effective dose and the toxic dose, requiring careful monitoring of serum drug levels and signs of toxicity. Drugs such as digoxin, lithium, and warfarin fall into this category, where minor dosage adjustments can lead to serious adverse effects.