— 藥理與非經腸給藥 · EASY · MCQ —
病人正接受肝素持續輸注，護理師應監測哪項檢驗值以評估療效？
A client is receiving heparin infusion. Which laboratory value should the nurse monitor to evaluate the effectiveness of the therapy?
- APlatelet count血小板計數
- BActivated partial thromboplastin time (aPTT)✓ 正解活化部分凝血活酶時間 (aPTT)
- CProthrombin time (PT)凝血酶原時間 (PT)
- DInternational Normalized Ratio (INR)國際標準化比值 (INR)
— Explanation · 中文詳解 —
肝素（Heparin）的作用機轉是抑制凝血因子，其療效監測指標為 aPTT。通常目標值為正常對照值的 1.5 到 2.5 倍。PT/INR 用於監測 Warfarin 的療效，血小板則是監測肝素誘導之血小板低下症（HIT）。
The mechanism of heparin is inhibition of coagulation factors, and the laboratory parameter used to monitor its therapeutic effect is the aPTT. The target value is generally 1.5-2.5 times the normal control. PT/INR is used to monitor warfarin therapy, and the platelet count is used to monitor for heparin-induced thrombocytopenia (HIT).
✦ 台美臨床差異
兩地臨床皆依據 aPTT 調整肝素劑量，遵循嚴格的 Nomogram。