— 藥理與非經腸給藥 · EASY · MCQ —
病人服用華法林(Warfarin)。護理師應優先監測哪項檢驗數值以評估藥物療效?
A client is prescribed Warfarin. Which lab value should the nurse prioritize to monitor for therapeutic efficacy?
- AHgb/Hct血色素/血球容積比
- BPlatelet count血小板計數
- CPT/INR✓ 正解凝血酶原時間/國際標準化比值
- DaPTT活化部分凝血活酶時間
— Explanation · 中文詳解 —
華法林主要影響外源性凝血路徑,臨床上以凝血酶原時間(PT)及其標準化比值(INR)作為監測指標。通常目標 INR 範圍在 2.0-3.0 之間,需依據適應症調整。若數值過低表示抗凝血不足,過高則有出血風險,需定期抽血調整劑量。
Warfarin primarily affects the extrinsic coagulation pathway, and prothrombin time (PT) with its standardized ratio (INR) is used clinically as the monitoring parameter. The target INR range is typically 2.0-3.0, adjusted based on the indication. A value that is too low indicates inadequate anticoagulation, while a value that is too high carries a bleeding risk; periodic blood sampling is therefore required for dose titration.
✦ 台美臨床差異
台美兩地皆以 INR 為標準,但美國許多診所設有抗凝血劑門診由藥師主導劑量調整,台灣則多由醫師決定。