一位重度憂鬱症病人服用氟西汀（Fluoxetine）兩週後表示：「我感覺還是跟以前一樣悲傷。」護理師最適當的回答為何？
A client diagnosed with major depressive disorder has been on fluoxetine for 2 weeks. The client states, 'I still feel just as sad as before.' What is the most appropriate response by the nurse?
- AIt sounds like you need a higher dose of the medication聽起來你需要增加藥物劑量
- BMaybe we should discuss alternative treatments with the physician也許我們應該與醫師討論替代治療方案
- CAntidepressants can take 4 to 6 weeks to show full therapeutic effects✓ 正解抗憂鬱劑可能需要 4 到 6 週才能發揮完整的治療效果
- DHave you been taking the medication every single day?你有每天按時服藥嗎？
SSRIs 類藥物通常需要 4-6 週才能達到臨床療效。病人兩週無效是常見情況。護理師應給予正確衛教，緩解病人的挫折感。建議增加劑量或換藥應由醫師根據後續評估決定，護理師不應過早引導病人質疑藥物療效。
SSRIs typically require 4 to 6 weeks to achieve full clinical effect. It is common for the client to feel no improvement after 2 weeks. The nurse should provide accurate education to relieve the client's frustration. Suggestions to increase the dose or change medication should be made by the physician after subsequent evaluation, and the nurse should not prematurely lead the client to doubt the drug's effectiveness.
台灣病人對藥物依從性要求較高，常因預期效果過快而中斷治療，衛教時間通常較短。