— 藥理與非經腸給藥 · MEDIUM · MCQ —
護理師給予皮下注射甘精胰島素（Glargine），下列哪項措施正確？
A nurse is administering subcutaneous insulin glargine. Which action by the nurse is correct?
- AAdminister at the same time each day✓ 正解每日固定時間給藥
- BShake the vial vigorously before drawing抽取藥液前用力搖晃安瓿瓶
- CEnsure the site is massaged after injection確保注射後按摩注射部位
- DMix with regular insulin in the same syringe於同一支針筒內與常規胰島素混合
— Explanation · 中文詳解 —
甘精胰島素（Insulin glargine）屬於長效型胰島素，其機轉是提供 24 小時穩定的基礎血糖控制，不會產生明顯的峰值。給藥的核心在於「穩定性」，因此必須固定時間給藥。臨床思路應強調此藥物不能與其他胰島素混合，因為其酸鹼值不同，混合會導致藥效改變。給藥時應嚴格遵守固定時間，以維持體內恆定的胰島素濃度。
Insulin glargine is a long-acting insulin; its mechanism provides 24 hours of steady basal glycemic control without producing a noticeable peak. The core of administration is consistency, so it must be given at the same time each day. Clinically, this medication must not be mixed with any other insulin because of pH differences; mixing alters drug effect. Administration must adhere strictly to a fixed schedule to maintain a constant level of insulin in the body.