— 藥理與非經腸給藥 · MEDIUM · MCQ —
一位病人正在接受萬古黴素的連續輸注。護理師應監測哪個實驗室數值以評估潛在的腎毒性？
A client is receiving a continuous infusion of vancomycin. The nurse should monitor which laboratory value for potential nephrotoxicity?
- AHemoglobin A1c (HbA1c)糖化血色素 (HbA1c)
- BCreatinine✓ 正解肌酸酐
- CProthrombin time (PT)凝血酶原時間 (PT)
- DAspartate aminotransferase (AST)天門冬胺酸轉氨酶 (AST)
— Explanation · 中文詳解 —
萬古黴素是一種已知可能引起腎毒性的抗生素。監測血清肌酐 (creatinine) 是評估腎功能的最常用指標，肌酐升高表示腎臟清除能力下降。AST 主要反映肝功能，HbA1c 反映長期血糖控制，PT 反映外源性凝血途徑。
Vancomycin is known for its potential nephrotoxicity, so monitoring serum creatinine levels is essential to detect early signs of kidney dysfunction. Elevated creatinine indicates decreased glomerular filtration rate, allowing for timely intervention to prevent further renal damage while the client receives this antibiotic therapy.
✦ 台美臨床差異
美國的藥物監測指南對萬古黴素的腎功能監測有嚴格規定；台灣的監測頻率和標準也類似，但會視個別病人情況調整。