護理師正準備給予哌拉西林-他唑巴坦（piperacillin-tazobactam）的靜脈輸注。病人已知對盤尼西林（penicillin）過敏。首要的護理措施為何？
A nurse is preparing to administer an IV infusion of piperacillin-tazobactam. The client has a known allergy to penicillin. What is the priority nursing action?
- AAdminister a test dose first.先给予测试剂量
- BHold the medication and notify the physician.✓ 正解暂停给药并通知医师
- CAdminister the medication with an antihistamine.给予抗组织胺的同时给药
- DAdminister the medication as prescribed.依处方给药
Piperacillin-tazobactam 屬於廣效性盤尼西林類抗生素。對於有盤尼西林過敏史的病人，給予此藥可能引發交叉過敏反應，甚至導致致命的過敏性休克（anaphylaxis）。護理師的核心責任是確保用藥安全（Safety），當病人有過敏史時，護理師必須採取預防措施，先行暫停給藥並聯繫醫師確認處方的適當性與風險效益，這是防止藥物不良反應的首要步驟。
Piperacillin-tazobactam is a broad-spectrum penicillin-class antibiotic. In a client with a known penicillin allergy, administration can trigger a cross-reactive allergic response, including potentially fatal anaphylaxis. The nurse's central responsibility is to ensure medication safety: when an allergy history is documented, the nurse must hold the drug and contact the physician to verify the appropriateness and risk-benefit of the order. This is the essential first step in preventing serious adverse drug reactions.