— 藥理與非經腸給藥 · MEDIUM · MCQ —
病人因深層靜脈血栓正接受肝素（Heparin）輸注。護理師應監測哪項數據以評估治療成效？
A client is receiving heparin infusion for deep vein thrombosis. Which lab value should the nurse monitor to evaluate therapeutic effectiveness?
- APlatelet count血小板計數
- BActivated partial thromboplastin time (aPTT)✓ 正解活化部分凝血活酶時間 (aPTT)
- CInternational Normalized Ratio (INR)國際標準化比值 (INR)
- DProthrombin time (PT)凝血酶原時間 (PT)
— Explanation · 中文詳解 —
肝素（Heparin）透過抑制凝血因子來發揮作用，臨床上透過 aPTT 來監測其抗凝血效果。PT 與 INR 主要用於評估口服抗凝血劑如 Warfarin。雖然血小板計數在肝素治療中很重要（需監測 HIT），但其並非評估肝素抗凝血成效的指標。
Heparin inhibits coagulation factors; therapeutic effect is monitored by aPTT. PT and INR primarily monitor oral anticoagulants like warfarin. Platelet count matters during heparin therapy (to detect HIT) but is not the indicator of therapeutic anticoagulation.
✦ 台美臨床差異
美台臨床皆高度依賴 aPTT 調整輸注速率，並使用 Nomogram（流速調整表）。