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藥理與非經腸給藥 · MEDIUM · SATA

護理師指導病人使用舌下硝化甘油(Nitroglycerin)治療心絞痛,應包含哪些內容?(選所有適合的)

A nurse is teaching a client about the use of sublingual nitroglycerin for angina. Which of the following instructions should be included? (Select all that apply.)

  • AKeep the tablets in the original amber glass bottle✓ 正解
    將錠劑保存在原廠棕色玻璃瓶中
  • BTake one tablet every 5 minutes for up to three doses✓ 正解
    每5分鐘服用一錠,最多三劑
  • CSwallow the tablet immediately with a full glass of water
    立即以一滿杯水吞服錠劑
  • DIf pain persists after the first dose, call emergency services✓ 正解
    若第一劑後疼痛未緩解,請撥打緊急服務電話
  • ECarry the medication in your pocket at all times
    隨時將藥物放在口袋中攜帶
Explanation · 中文詳解

舌下硝化甘油對光敏感,必須儲存在原裝遮光玻璃瓶內。若心絞痛發作,建議每 5 分鐘服用一劑,最多 3 劑,若第一劑後症狀未緩解或加劇,應立即撥打緊急救援電話。此藥為舌下吸收,不可吞服,否則會經過肝臟代謝導致藥效大減。

Sublingual nitroglycerin is light-sensitive and must be stored in its original amber glass bottle. For angina, one tablet may be taken every 5 minutes for up to three doses; if symptoms do not improve or worsen after the first dose, emergency services should be called immediately. The drug is absorbed sublingually and must not be swallowed, as first-pass hepatic metabolism would substantially reduce its effect.

✦ 台美臨床差異

在台灣,針對硝化甘油的衛教多強調「每 5 分鐘服用一次」,且若未緩解需立即就醫,與美國指引一致。

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