護理師正在照顧一位新診斷為結核病（TB）的病人。該病人被處方使用異煙肼（isoniazid）。護理師應提供關於潛在副作用的哪項重要指導？
A nurse is caring for a client with a new diagnosis of tuberculosis (TB). The client is prescribed isoniazid. Which instruction is essential for the nurse to provide regarding potential side effects?
- AMonitor blood glucose levels daily每日監測血糖
- BAvoid consuming aged cheese避免食用陳年乳酪
- CTake the medication with milk to reduce stomach upset隨牛奶服用藥物以減少胃部不適
- DReport any numbness or tingling in the hands or feet✓ 正解報告手或腳的任何麻木或刺痛感
異煙肼（Isoniazid）是治療結核病的一線藥物，其主要的嚴重副作用是周邊神經炎（Peripheral neuritis），這是因為藥物會拮抗維生素 B6（Pyridoxine）的代謝，導致神經毒性。病人可能會感受到手腳麻木、刺痛或燒灼感。在教學上，護理師必須強調這些早期徵兆，以便即時補充維生素 B6 來預防神經損傷，這是預防醫療併發症的關鍵。
Isoniazid is a first-line drug for the treatment of tuberculosis, and its main serious adverse effect is peripheral neuritis. This occurs because the drug antagonizes the metabolism of vitamin B6 (pyridoxine), leading to neurotoxicity. Clients may experience numbness, tingling, or burning sensations in the hands and feet. The nurse must emphasize these early signs during teaching so that vitamin B6 supplementation can be initiated promptly to prevent nerve damage, which is key to preventing iatrogenic complications.
在美國臨床實務中，給予異煙肼時，通常會常規性地同時處方維生素 B6（Pyridoxine）以預防副作用，此為標準預防措施。