— 生理適應 · MEDIUM · MCQ —
慢性腎臟病病人服用紅血球生成素(epoetin alfa),哪項數據顯示治療有效?
A client with chronic kidney disease is prescribed epoetin alfa. Which assessment finding indicates effectiveness?
- AImproved urine output尿量增加
- BDecreased blood pressure血壓下降
- CIncreased hemoglobin level✓ 正解血紅素濃度上升
- DReduced serum creatinine血清肌酸酐降低
— Explanation · 中文詳解 —
Epoetin alfa 的作用機轉是刺激骨髓產生紅血球,用於治療因腎臟分泌紅血球生成素不足導致的貧血。當血紅素(Hemoglobin)濃度上升,代表藥物達成改善貧血的目標。此藥對腎功能指標如肌酸酐無直接緩解作用。
The mechanism of action of epoetin alfa is to stimulate bone marrow production of red blood cells; it is used to treat anemia caused by inadequate renal erythropoietin production. When the hemoglobin level rises, the drug has achieved its goal of treating the anemia. This medication has no direct effect on renal function markers such as creatinine.
✦ 台美臨床差異
在兩地臨床,此藥均需密切監控血壓波動,以防高血壓危象。