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藥理與非經腸給藥 · MEDIUM · MCQ

一位孕婦因子癇症(Eclampsia)接受硫酸鎂輸注。哪項發現需要立即介入?

A client is receiving an infusion of magnesium sulfate for eclampsia. Which finding requires immediate intervention?

  • ARespiratory rate is 14 breaths per minute
    呼吸頻率為每分鐘 14 次
  • BClient reports a feeling of warmth
    病人表示有溫暖感
  • CDeep tendon reflexes are 1+✓ 正解
    深部肌腱反射為 1+
  • DSerum magnesium level is 6.5 mg/dL
    血清鎂濃度為 6.5 mg/dL
Explanation · 中文詳解

硫酸鎂(Magnesium sulfate)用於治療子癇前症(Preeclampsia)時,具有神經肌肉抑制作用。中毒的三大徵兆為深部肌腱反射(DTR)消失、呼吸抑制(<12次/分)與尿量減少(<30ml/hr)。1+ 反射代表反射減弱,為早期中毒跡象,護理師需立即停藥並通知醫師,以避免進展為嚴重的呼吸抑制。

Magnesium sulfate used for preeclampsia/eclampsia causes neuromuscular depression. The three classic signs of toxicity are loss or diminution of deep tendon reflexes, respiratory depression (<12 breaths/min), and decreased urine output (<30 mL/hr). A 1+ DTR represents diminished reflexes and is an early warning of toxicity—the nurse must hold the drug and notify the provider to prevent progression to severe respiratory depression.

✦ 台美臨床差異

美國臨床護理中,硫酸鎂給藥期間通常會要求使用輸液幫浦,並每小時監測生命徵象與反射,且床邊必須備有鈣離子拮抗劑(Calcium gluconate)作為解毒劑。

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