— 藥理與非經腸給藥 · EASY · SATA —
病人服用 Furosemide 治療心衰竭，下列何者顯示該藥物有效？（選所有適合的）
A client is prescribed furosemide for heart failure. Which findings would indicate to the nurse that the medication is effective? (Select all that apply.)
- AIncreased urine output✓ 正解尿量增加
- BDecrease in peripheral edema✓ 正解周邊水腫減少
- CWeight loss of 2 lbs in 24 hours✓ 正解24 小時內體重減輕 2 磅
- DDecrease in blood pressure血壓下降
- EImproved lung sounds (clearer breath sounds)✓ 正解肺部聽診聲音改善（呼吸音較清晰）
— Explanation · 中文詳解 —
Furosemide 是強效利尿劑，有效指標為尿量增加、周邊水腫改善、肺部濕囉音（crackles）減少以及體重因水分排出而減輕。血壓下降雖為藥物作用之一，但並非評估心衰竭改善的「治療指標」，且利尿過快可能造成血壓過低。
Furosemide is a potent diuretic, and effective indicators include increased urine output, reduced peripheral edema, decreased pulmonary crackles, and weight loss from fluid removal. Although a decrease in blood pressure is one of the drug's effects, it is not considered a therapeutic indicator of heart failure improvement, and overly rapid diuresis can cause hypotension.
✦ 台美臨床差異
兩地對於心衰竭藥物療效評估指標基本一致，均將肺音改善視為重要臨床指標。