護理師準備給藥。若病人有下列何種狀況，應對給予 Beta-blocker 提出疑義？
A nurse is preparing to administer several medications. Which client condition requires the nurse to question the administration of a prescribed beta-blocker?
- AChronic stable angina慢性穩定型心絞痛
- BType 2 diabetes mellitus第二型糖尿病
- CHistory of hypertension高血壓病史
- DPresence of bronchial asthma✓ 正解支氣管氣喘
Beta-blocker（特別是非選擇性類）會阻斷支氣管平滑肌上的 Beta-2 受體，引起支氣管收縮。對於氣喘病人，這可能誘發嚴重的呼吸窘迫或氣喘發作。因此，患有氣喘的病人使用此類藥物前，護理師需確認醫師是否開立了具有選擇性的 Beta-1 阻斷劑，或尋求替代藥物。
Beta-blockers, particularly non-selective agents, can block beta-2 receptors in the lungs, causing bronchoconstriction and potentially triggering severe respiratory distress in clients with asthma. Although beta-blockers are indicated for conditions like angina, diabetes, and hypertension, the presence of bronchial asthma is a significant contraindication that requires the nurse to verify the prescription or suggest an alternative. The nurse must prioritize airway safety by questioning orders that could compromise respiratory function in susceptible clients.
美台臨床皆將氣喘視為使用非選擇性 Beta-blocker 的重要警訊，醫師處方時需特別留意。