護理師照顧一位接受連續肝素滴注的病人。病人的基礎 aPTT 為 30 秒。下列哪個 aPTT 結果代表滴注在治療範圍內？
A nurse is caring for a client with a continuous heparin infusion. The client's baseline aPTT is 30 seconds. Which aPTT result indicates the infusion is in the therapeutic range?
- A55 seconds✓ 正解55 秒
- B35 seconds35 秒
- C95 seconds95 秒
- D120 seconds120 秒
肝素（Heparin）是一種常用的抗凝血劑，透過抑制凝血因子來預防血栓形成或擴大。當病人接受連續靜脈肝素滴注治療時，精確監測其抗凝血效果至關重要，以確保治療達到預期效果，同時避免出血併發症。活化部分凝血活酶時間（activated Partial Thromboplastin Time, aPTT）是監測肝素治療效果的主要指標。護理師必須了解肝素的治療性 aPTT 範圍，以便根據檢驗結果調整滴注速率，確保病人的凝血功能維持在安全的治療區間內。這項精確的監測和調整對於病人安全至關重要。
Heparin is a commonly used anticoagulant that inhibits clotting factors to prevent the formation or extension of thrombi. When a client is receiving a continuous IV heparin infusion, precise monitoring of the anticoagulant effect is essential to ensure the therapy achieves its intended effect while avoiding bleeding complications. The activated partial thromboplastin time (aPTT) is the primary indicator for monitoring heparin therapy. The nurse must understand the therapeutic aPTT range for heparin in order to titrate the infusion rate based on laboratory results, keeping the client's coagulation status within the safe therapeutic window. This precise monitoring and titration is critical to client safety.
肝素（Heparin）的連續靜脈滴注治療和其 aPTT 監測目標範圍，在台灣和美國的臨床實踐中是完全一致的。兩地都將治療性 aPTT 定義為基礎值或實驗室對照值的 1.5 到 2.5 倍，以確保抗凝血效果並降低出血風險。護理師會根據 aPTT 數值調整肝素滴注速率，這在兩地都是標準的護理常規。因此，此題的臨床實踐在兩地並無顯著差異。