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藥理與非經腸給藥 · MEDIUM · SATA

護理師準備給予病人地高辛(digoxin)。下列哪些發現需要暫停給藥並聯繫醫師?(選所有適合的)

A nurse is preparing to administer digoxin. Which client finding requires holding the dose and notifying the provider? (Select all that apply.)

  • AApical pulse 52 beats per minute✓ 正解
    心尖脈搏 52 次/分
  • BSerum potassium 3.2 mEq/L✓ 正解
    血清鉀離子 3.2 mEq/L
  • CVisual disturbances such as blurred vision✓ 正解
    視力障礙,例如視力模糊
  • DBlood pressure 110/70 mmHg
    血壓 110/70 mmHg
  • ESerum digoxin level 1.2 ng/mL
    血清地高辛濃度 1.2 ng/mL
Explanation · 中文詳解

地高辛(Digoxin)具有正性肌力與負性頻率作用,治療指數極窄,易發生洋地黃中毒(Digitalis toxicity)。護理評估重點在於偵測中毒徵兆與加重因子。心跳過慢(小於 60 bpm)會抑制傳導系統,低血鉀則會增加心肌細胞對地高辛的敏感度,兩者皆會顯著提高中毒風險。此外,神經毒性(如視力模糊、黃綠色視覺異常)是經典的臨床警訊。護理師給藥前必須檢查心跳速率、電解質數值及病人主訴,若有異常應立即暫停給藥並回報醫師。

Digoxin has positive inotropic and negative chronotropic effects, with a very narrow therapeutic index that predisposes to digitalis toxicity. The focus of nursing assessment is on detecting toxicity and its contributing factors. A heart rate below 60 bpm suppresses the conduction system, and hypokalemia increases myocardial sensitivity to digoxin; both significantly increase the risk of toxicity. Neurotoxic effects (such as blurred vision and yellow-green visual disturbances) are classic clinical warning signs. Before administering digoxin, the nurse must check the heart rate, electrolyte values, and the client's complaints; if any abnormalities are present, the dose should be held and the physician notified.

✦ 台美臨床差異

台灣與美國在給藥常規上皆要求給藥前監測心跳,但美國臨床護理實務對於地高辛的給藥流程非常嚴格,若心跳低於 60 下,護理師有明確的權限(Scope of Practice)暫停給藥並通知醫師,無需醫師開立額外醫囑。

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