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藥理與非經腸給藥 · MEDIUM · SATA

病人靜脈輸注萬古黴素(Vancomycin),下列哪些臨床表現提示「紅人症候群」?(選所有適合的)

A client is prescribed intravenous vancomycin. Which clinical signs suggest 'Red Man Syndrome' associated with the infusion? (Select all that apply.)

  • AHypotension✓ 正解
    低血壓
  • BFlushing of the face and neck✓ 正解
    臉部與頸部潮紅
  • CWheezing and throat swelling
    喘鳴與喉頭水腫
  • DPruritus and rash on the upper torso✓ 正解
    搔癢與上軀幹皮疹
  • ETachycardia✓ 正解
    心搏過速
Explanation · 中文詳解

紅人症候群(Red Man Syndrome)是由於萬古黴素輸注速度過快,導致組織胺釋放所引發的類過敏反應。其典型臨床表現包括上半身潮紅、搔癢、低血壓與心搏過速。需特別區分的是,此反應與真正的過敏性休克(Anaphylaxis,伴隨喉頭水腫、喘鳴)不同,治療重點在於減慢滴速或暫停輸注並給予抗組織胺。

Red Man Syndrome is an anaphylactoid reaction caused by histamine release when vancomycin is infused too quickly. Typical clinical manifestations include flushing of the upper body, pruritus, hypotension, and tachycardia. It is important to distinguish this reaction from true anaphylactic shock (which is accompanied by laryngeal edema and wheezing); treatment focuses on slowing or temporarily stopping the infusion and administering an antihistamine.

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