— 藥理與非經腸給藥 · EASY · MCQ —
一位病人正接受靜脈注射萬古黴素（Vancomycin），出現什麼臨床症狀提示發生「紅人症候群」？
A client is receiving vancomycin intravenously. Which clinical manifestation indicates the client is experiencing Red Man Syndrome?
- ASwelling of the tongue and throat舌頭與喉嚨水腫
- BDiffuse maculopapular rash on the lower extremities下肢瀰漫性斑丘疹
- CHypotension and wheezing低血壓與喘息
- DFlushing of the face, neck, and upper torso✓ 正解臉部、頸部及上半身潮紅
— Explanation · 中文詳解 —
紅人症候群（Red Man Syndrome）是由於萬古黴素（Vancomycin）輸注速度過快，導致組織胺（Histamine）大量釋放所引發的類過敏反應。其典型臨床表現為臉部、頸部及上半身出現紅斑或潮紅，有時伴隨搔癢與低血壓。這不是真正的 IgE 介導過敏，通常透過減慢輸注速率或暫停輸注即可緩解，必要時醫師會開立抗組織胺治療。
Red Man Syndrome is a histamine-mediated reaction caused by rapid vancomycin infusion, resulting in flushing of the face, neck, and upper torso. This is distinct from a true IgE-mediated allergy and typically resolves by slowing the infusion rate or temporarily stopping it.