— 藥理與非經腸給藥 · EASY · MCQ —
護理師準備對一名深部靜脈栓塞病史的病人給予華法林(warfarin),應查閱哪項實驗室數據?
A nurse is preparing to administer warfarin to a client with a history of deep vein thrombosis. Which laboratory value should the nurse review?
- APartial thromboplastin time (PTT)部分凝血活酶時間 (PTT)
- BInternational normalized ratio (INR)✓ 正解國際標準化比值 (INR)
- CProthrombin time (PT)凝血酶原時間 (PT)
- DPlatelet count血小板計數
— Explanation · 中文詳解 —
華法林透過抑制維生素 K 依賴性凝血因子發揮作用,臨床監測黃金標準為 INR。PT 雖然也會受影響,但因為試劑標準化差異,國際通用的 INR 數值能更精確反映治療範圍,避免不同實驗室誤差導致的劑量錯誤。
The International Normalized Ratio (INR) is the standardized laboratory test used to monitor warfarin therapy because it accounts for variations in prothrombin time reagents across different laboratories. While PT is affected, INR provides a consistent measure to ensure the dosage remains within the therapeutic range.
✦ 台美臨床差異
台美醫療體系皆以 INR 作為華法林監測標準,台灣健保對此項檢查有明確給付規範。