— 藥理與非經腸給藥 · EASY · MCQ —
護理師指導病人使用定量吸入劑（MDI）搭配儲霧器（Spacer）。其主要好處為何？
A nurse is teaching a client about the use of a spacer with an MDI. What is the main benefit?
- AImproves drug delivery to the lungs✓ 正解改善藥物遞送至肺部
- BEliminates the need to shake the inhaler免除搖晃吸入器的需要
- CIncreases the concentration of the drug增加藥物濃度
- DReduces the need for deep breathing減少深呼吸的需要
— Explanation · 中文詳解 —
定量吸入劑（MDI）若無儲霧器，藥物顆粒往往會噴射至口腔與咽喉後壁，導致大部分藥物沉降於上呼吸道，無法進入肺部深處。儲霧器（Spacer）的作用在於減緩藥物噴霧速度，讓霧粒在儲霧腔內懸浮，病人可透過深慢呼吸將藥物吸入肺部，顯著提升藥物在肺部的沉積率，並減少因藥物殘留口腔而引起的副作用（如類固醇引起的鵝口瘡）。
Using a spacer with a metered-dose inhaler improves drug delivery to the lungs by slowing the aerosol spray and allowing particles to remain suspended for deeper inhalation. This technique reduces the amount of medication deposited in the oropharynx, thereby minimizing local side effects such as oral thrush. It ensures that a greater proportion of the therapeutic dose reaches the lower respiratory tract.