— 藥理與非經腸給藥 · EASY · MCQ —
肝素 (Heparin) 這類抗凝血藥物的主要作用是什麼?
What is the primary action of an anticoagulant like Heparin?
- ADecreases platelet production減少血小板生成
- BIncreases fibrinolysis增加纖維蛋白溶解
- CPrevents the formation of new clots✓ 正解防止新血栓形成
- DDissolves existing thrombi溶解現有血栓
— Explanation · 中文詳解 —
肝素(Heparin)是一種抗凝血劑(Anticoagulant),其機轉是透過活化抗凝血酶 III(Antithrombin III)來抑制凝血酶(Thrombin)及第 Xa 凝血因子的活性,從而阻斷纖維蛋白原轉變為纖維蛋白的過程。因此,肝素的主要作用是預防新血栓的形成,並防止現有血栓擴大,但它本身並沒有溶解已形成血栓的能力(此為溶栓劑的功能)。
Heparin functions as an anticoagulant by enhancing the activity of antithrombin III, which inhibits clotting factors and prevents the formation of new thrombi. It stops existing clots from enlarging but does not actively dissolve already formed clots, a process reserved for thrombolytic agents.